19 julho 2015

ofmicrobesandmen: Sporozoites of the...



ofmicrobesandmen:

Sporozoites of the parasite Cryptosporidium parvum emerging from their oocyst to infect gastrointestinal epithelial cells.

Cryptosporidium, commonly known by the comic book supervillian name “Crypto,” is commonly transmitted by ingesting water or food contaminated with Crypto oocysts. Once ingested, the oocyte ruptures, and the sporozoites contained within infect the gut of their new host, causing watery diarrhea. 

Though outbreaks occasionally occur in the developed world, few infected in those outbreaks die from Crypto. However, in the developing world, some of those infected with Crypto develop chronic disease and die, particularly small, malnourished children.

For more on Crypto and how scientists are tackling this tricky parasite, check out this article on NPR’s All Things Considered about the work being done by the Striepen lab at the University of Georgia Center for Tropical and Emerging Global Diseases.

Image courtesy Boris Striepen and Muthgapatti Kandasamy, University of Georgia Center for Tropical and Emerging Global Diseases

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